gene

RAD52

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RAD52: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

9Connections

0Hypotheses

0Analyses

6Outgoing

3Incoming

Summary

RAD52 — DNA Repair Protein

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🧬 Gene Info

Gene Symbol	RAD52
Full Name	RAD52 Homologous Recombination Repair Protein
Aliases	DNA Repair Protein
Chromosome	12p13.33
Function	RAD52 is a key protein in the homologous recombination (HR) pathway of DNA double-strand break (DSB) repair.
UniProt ID	P43369
NCBI Gene ID	5888
Ensembl ID	ENSG00000102038
GeneCards	RAD52
Human Protein Atlas	RAD52
Associated Diseases	Aging
Interactions	RAD50
KG Connections	9 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: RAD52 — AlphaFold P43369 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (5)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    RAD52["RAD52"]
    Aging["Aging"]
    DRP1["DRP1"]
    RAD50["RAD50"]
    neurodegeneration["neurodegeneration"]

    RAD52 -->|"associated with"| Aging
    DRP1 -->|"associated with"| RAD52
    RAD50 -->|"interacts with"| RAD52
    RAD52 -->|"implicated in"| neurodegeneration

    style RAD52 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
    style Aging fill:#3e1a1a,stroke:#ef5350,stroke-width:2px,color:#fff
    style DRP1 fill:#1a237e,stroke:#ce93d8,stroke-width:2px,color:#fff
    style RAD50 fill:#1a237e,stroke:#ce93d8,stroke-width:2px,color:#fff
    style neurodegeneration fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff

Outgoing (6)

Target	Relation	Type	Str
Aging	associated_with	disease	0.65
SETX	causes	gene	0.60
XPF	causes	gene	0.60
SETX	targets	gene	0.60
XPF	targets	gene	0.60
RNA	causes	gene	0.60

Incoming (3)

Source	Relation	Type	Str
DRP1	associated_with	gene	0.60
RAD50	interacts_with	gene	0.60
DNA	causes	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found