| Gene Symbol | SETDB1 |
| Full Name | SET Domain Bifurcated Histone Lysine Methyltransferase 1 |
| Aliases | SETDB1PROTEIN |
| Chromosome | 1q21.3 |
| Protein Type | Transferase |
| Function | encodes a histone H3 lysine 9 (H3K9) methyltransferase that catalyzes mono-, di-, and trimethylation of H3K9. |
| Subcellular Localization | ** | Nucleus | |
| UniProt ID | Q15047 |
| Ensembl ID | ENSG00000143379 |
| OMIM | 604396 |
| GeneCards | SETDB1 |
| Human Protein Atlas | SETDB1 |
| Phosphorylation | Multiple phosphorylation sites regulate SETDB1 activity and protein-protein interactions |
| Acetylation | Lysine acetylation can regulate SETDB1 targeting and function |
| Sumoylation | SUMO modification of SETDB1 influences its transcriptional repressive function |
| Associated Diseases | Leukemia |
| Interactions | AND, CGAS-STING |
| KG Connections | 11 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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