| Gene Symbol | SIL1 |
| Full Name | SIL1 Nucleotide Exchange Factor |
| Chromosome | 5q31.2 |
| Protein Family | Hsp70 co-chaperones, NEF family |
| Protein Type | Chaperone |
| Function | By stimulating ATP hydrolysis and substrate release from BiP, SIL1 facilitates the protein folding cycle in the ER lumen. |
| Subcellular Localization | Endoplasmic reticulum (lumen) |
| Molecular Weight | ~52 kDa |
| UniProt ID | Q9H3K5 |
| NCBI Gene ID | 22954 |
| Ensembl ID | ENSG00000135902 |
| OMIM | 608005 |
| GeneCards | SIL1 |
| Human Protein Atlas | SIL1 |
| Protein Name | SIL1 |
| Associated Diseases | Ataxia, Ms |
| KG Connections | 19 knowledge graph edges |
| Databases | GeneCardsHPASTRING |