| Gene Symbol | SYNGAP1 |
| Full Name | Synaptic Ras GTPase Activating Protein 1 |
| Aliases | SYNGAP1PROTEIN |
| Chromosome | 6p21.3 |
| Function | is a major postsynaptic density (PSD) protein that regulates Ras signaling and controls AMPA receptor trafficking, making it essential for synaptic plasticity, learning, and memory. |
| Primary Expression | Brain (cortex, hippocampus), postsynaptic densities |
| Subcellular Localization | </strong></td><td>Postsynaptic density, cytoplasm</td></tr> |
| Molecular Weight | 150 kDa |
| Amino Acids | 1343 aa |
| UniProt ID | [Q9ULB0](https://www.uniprot.org/uniprot/Q9ULB0) |
| Ensembl ID | ENSG00000197283 |
| OMIM | 603384 |
| GeneCards | SYNGAP1 |
| Human Protein Atlas | SYNGAP1 |
| Associated Diseases | neurodegeneration |
| Interactions | ERK, STXBP1, RAS |
| SciDEX Hypotheses | Interneuron SYNGAP1 Deficiency Disrupts Cortical C |
| KG Connections | 18 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |