| Gene Symbol | TAC1PROTEIN |
| Chromosome | 7q21 |
| Function | The tachykinin system represents one of the oldest neuropeptide signaling systems in evolution, with conserved functions across species from amphibians to humans. |
| Primary Expression | distinct neuronal populations within the basal ganglia, cortex, hippocampus, and brainstem, where they modulate dopaminergic signaling, GABAergic tran |
| Molecular Weight | 17 kDa |
| Amino Acids | 11 aa |
| GeneCards | TAC1PROTEIN |
| Human Protein Atlas | TAC1PROTEIN |
| Receptor | Primary Ligand |
| NK1R (TACR1) | Substance P |
| NK2R (TACR2) | Neurokinin A |
| NK3R (TACR3) | Neurokinin B |
| Compound | Indication |
| Aprepitant | AD |
| NK1 antagonist | PD |
| Associated Diseases | neurodegeneration |
| Interactions | TRPM8, WNT3A |
| KG Connections | 27 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |