WNT3A

Understanding Entity Pages

This page aggregates everything SciDEX knows about WNT3A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

WNT3A is a gene implicated in neurodegeneration research. Key relationships include: inhibits, activates, expressed in. Associated with ALS, Als, Alzheimer. Connected to 26 entities in the SciDEX knowledge graph.

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graph TD
    WNT3A["<b>WNT3A</b>"]
    Cancer{"Cancer"}
    WNT3A -->|"activates"| Cancer
    Inflammation{"Inflammation"}
    WNT3A -->|"expressed in"| Inflammation
    ALS{"ALS"}
    WNT3A -->|"inhibits"| ALS
    Alzheimer{"Alzheimer"}
    WNT3A -->|"inhibits"| Alzheimer
    WNT3A -->|"inhibits"| Cancer
    P38["P38"]
    WNT3A -->|"activates"| P38
    Wnt(["Wnt"])
    WNT3A -->|"activates"| Wnt
    Mapk(["Mapk"])
    WNT3A -->|"activates"| Mapk
    INFLAMMATION["INFLAMMATION"]
    WNT3A -->|"expressed in"| INFLAMMATION
    Epigenetic(["Epigenetic"])
    WNT3A -->|"inhibits"| Epigenetic
    WNT3A -->|"inhibits"| Wnt
    CANCER["CANCER"]
    WNT3A -->|"inhibits"| CANCER
    KLF14["KLF14"]
    KLF14 -->|"inhibits"| WNT3A
    CANCER -->|"activates"| WNT3A
    LRP6["LRP6"]
    LRP6 -->|"inhibits"| WNT3A
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"inhibits"| WNT3A
    ALZHEIMER["ALZHEIMER"]
    ALZHEIMER -->|"inhibits"| WNT3A
    CANCER -->|"inhibits"| WNT3A
    AND["AND"]
    AND -->|"inhibits"| WNT3A
    HDAC["HDAC"]
    HDAC -->|"inhibits"| WNT3A
    style WNT3A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0