protein 2,134 words KG: UGDH
Contents

UDP-Glucose 6-Dehydrogenase (UGDH) Protein

🔬 Protein Info
Gene SymbolUDP
Full NameGlucose 6-Dehydrogenase (UGDH) Protein
AliasesUGDH: UDP-Glucose 6-Dehydrogenase
Chromosome4p15.1
Protein TypeEnzyme
Functionis a crucial NAD-dependent enzyme that catalyzes the oxidation of UDP-glucose to UDP-glucuronic acid, a key precursor for glycosaminoglycan (GAG) biosynthesis[@barash1999][@wang2000].
Primary Expressionboth neurons and glia, where it contributes to the maintenance of extracellular matrix integrity, neuroinflammation regulation, and cellular stress re
Subcellular Localization</th><td>Cytoplasm</td></tr>
Molecular Weight52 kDa
Amino Acids463 aa
Exons11
UniProt ID[Q9Y2K2](https://www.uniprot.org/uniprot/Q9Y2K2)
Ensembl IDENSG00000108639
GeneCardsUDP
Human Protein AtlasUDP
Associated DiseasesAlzheimer's disease, Parkinson's disease
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.