protein 1,315 words KG: VASOPRESSINPROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

Arginine Vasopressin (AVP)

🔬 Protein Info
Gene SymbolAVP
AliasesVASOPRESSINPROTEIN
Chromosome20p13
FunctionThe AVP gene encodes preprovasopressin, which is processed to mature AVP (arginine vasopressin) along with neurophysin I and a glycopeptide.
Primary Expressionbrain regions involved in social and homeostatic functions:
Subcellular Localization</strong> Secretory vesicles, dense-core granules</div>
PathwaysChaperone
Ensembl IDENSG00000101290
GeneCardsAVP
Human Protein AtlasAVP
SRX246A selective V1a antagonist being developed for stress-related disorders including PTSD and anxiety.
NelivaptanA V1a antagonist with potential CNS applications.
RelcovaptanA V1a antagonist explored for cardiovascular and CNS applications.
SSR149415A V1b antagonist with anxiolytic and antidepressant-like effects in preclinical models.
A-987180A selective V1b antagonist being developed for depression and stress disorders.
Associated DiseasesAlzheimer, Cancer, Cardiovascular, Diabetes, Hypertension, neurodegeneration
InteractionsACTH
KG Connections3 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph