Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ACTH: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Corticosteroids | activates | compound | 0.90 |
| Corticosterone | upregulates | compound | 0.90 |
| CORTISOL | activates | protein | 0.87 |
| Alopecia Areata | biomarker_for | disease | 0.80 |
| CORT | activates | protein | 0.72 |
| Source | Relation | Type | Str |
|---|---|---|---|
| CRH | activates | protein | 1.00 |
| AVP | associated_with | protein | 0.90 |
| CRH | stimulates | protein | 0.90 |
| POMC | associated_with | gene | 0.90 |
| OXT | inhibits | protein | 0.85 |
| POMC | product_of | gene | 0.85 |
| Alopecia Areata | biomarker_for | disease | 0.85 |
| VASOPRESSIN | stimulates | protein | 0.80 |
| VASOPRESSIN | activates | protein | 0.68 |
| OXYTOCIN | inhibits | protein | 0.64 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||