| Gene Symbol | VPS29PROTEIN |
| Function | is a core subunit of the retromer complex, a crucial protein complex involved in retrograde transport from endosomes to the trans-Golgi network (TGN) and the cell surface. |
| Subcellular Localization | ** Endosomes, trans-Golgi network, cytoplasm ``` ## Structure VPS29 is a 182-a |
| Molecular Weight | 18 kDa |
| GeneCards | VPS29PROTEIN |
| Human Protein Atlas | VPS29PROTEIN |
| N-terminal domain | Flexible region involved in protein interactions |
| Central scaffold domain | Forms the core structural framework |
| C-terminal region | Mediates interaction with VPS35 |
| VPS26 | Cargo recognition subunit (VPS26A or VPS26B) |
| VPS35 | Large scaffolding subunit |
| VPS29 | Structural scaffold and regulatory subunit |
| Associated Diseases | neurodegeneration |
| Interactions | ALZHEIMER, ALZHEIMER'S DISEASE, AND, App, GENES, GENETIC MODIFIERS |
| KG Connections | 43 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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