| Gene Symbol | TFEC |
| Full Name | Transcription Factor EC |
| Chromosome | 6p21.1 |
| Protein Family | bHLH-Zip (MITF/TFEB/TFE3/TFEC) |
| Function | Lysosomal biogenesis, autophagy regulation |
| Primary Expression | Microglia, brain macrophages |
| Pathways | pathway:
```mermaid, mTOR |
| GeneCards | TFEC |
| Human Protein Atlas | TFEC |
| Category | Target Genes |
| Lysosomal function | LAMP1, LAMP2, CTSD, GAA |
| Autophagy | LC3, ATG14, BECN1, SQSTM1 |
| Lipid metabolism | PGC1α, PPARα |
| Immune response | TREM2, CD68, CX3CR1 |
| Feature | TFEC |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |