| Gene Symbol | ent-gene-8c4b5215 |
| Disease State | Baseline sTREM2 |
| Alzheimer's Disease | Variable |
| Parkinson's Disease | Elevated |
| CBS/PSP | Elevated |
| Preclinical AD | Normal-high |
| Biomarker | Sample Type |
| GFAP | Plasma |
| sTREM2 | CSF |
| [NfL](/biomarkers/neurofilament-light-chain-nfl) | Plasma |
| YKL-40 | CSF |
| IL-6 | Plasma |
| TNF-α | Plasma |
| Drug | Target |
| AL002 (Alector) | TREM2 agonist |
| AL003 | TREM2 agonist |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |