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Epigenetic reprogramming in aging neurons

analysis Created: 2026-04-10T17:46:29 By: crosslink-v2 Quality: 50% ✓ SciDEX ID: analysis-SDA-2026-04-04-gap-epigenetic-r

Linked Artifacts (179)

derives_from📓Epigenetic reprogramming in aging neurons — Notebook Stub100%

produces📓Epigenetic reprogramming in aging neurons — Notebook Stub100%

mentions📖DNA Methylation Biomarkers in Neurodegeneration75%

mentions📖DNA Damage-Accumulating Neurons in Neurodegeneration75%

mentions📖DNA Damage and Repair in Neurons75%

mentions📖DNA Damage Response in Corticobasal Syndrome75%

mentions📖DNA Methylation75%

mentions📖DNA Damage Repair Deficiency Validation Study in Parkinson&#75%

mentions📖DNA Damage Repair Deficiency Hypothesis in Parkinson's 75%

mentions📖DNA Damage Repair Therapy - Biomarker Guided75%

mentions📖DNA Damage Repair Investment Landscape75%

mentions📖DNA Damage Response in Alzheimer's Disease75%

mentions📖dna-damage-repair75%

mentions📖DNA Damage Repair Mechanisms Across Neurodegenerative Diseas75%

mentions📖DNA Damage Response Impairment Pathway75%

mentions📖DNA Damage Response in 4R-Tauopathies75%

mentions📖DNA Damage Response in Alzheimer's Disease75%

mentions📖DNA Damage Response in Corticobasal Syndrome75%

mentions📖DNA Damage Response and Repair in Neurodegeneration75%

mentions📖DNA Damage Response in Neurons75%

mentions📖DNA Damage Response in Parkinson's Disease75%

mentions📖DNA Damage Response in Neurodegeneration75%

mentions📖DNA Methylation in Neurodegeneration75%

mentions📖DNA Repair Mechanisms in Neurodegeneration75%

mentions📖DNA Sensing Pathways in Neurodegeneration75%

mentions📖DNA Damage and Repair Dysfunction in PSP75%

mentions📖DNA Ligase III Protein75%

mentions📖DNA Ligase IV Protein75%

mentions📖DNA-PKcs (PRKDC) Protein75%

mentions📖DNA Damage Repair Therapy for Neurodegeneration75%

mentions📖DNA Repair Therapy for Neurodegeneration75%

related📖Mitochondria70%

related📖Mitochondria-Lysosome Contact Site Dysfunction in Parkinson&70%

related📖Mitochondria-Lysosome Contact Site (MLCS) Dysfunction Hypoth70%

related📖Mitochondria-Lysosome Contact Sites Dysfunction in Parkinson70%

related📖Mitochondria-Lysosome Contact Site Dysfunction in Parkinson&70%

related📖Mitochondria-Lysosome Contact Sites (MLCS) in Neurodegenerat70%

related📖Mitochondria in Neurodegeneration70%

related📖Mitochondria-Lysosome Contact Sites in Parkinson's Dise70%

related📖DNA Methylation Biomarkers in Neurodegeneration67%

related📖DNA Damage-Accumulating Neurons in Neurodegeneration67%

related📖DNA Damage and Repair in Neurons67%

related📖DNA Damage Response in Corticobasal Syndrome67%

related📖DNA Methylation67%

related📖DNA Damage Repair Deficiency Validation Study in Parkinson&#67%

related📖DNA Damage Repair Deficiency Hypothesis in Parkinson's 67%

related📖DNA Damage Repair Therapy - Biomarker Guided67%

related📖DNA Damage Repair Investment Landscape67%

related📖DNA Damage Response in Alzheimer's Disease67%

related📖dna-damage-repair67%

related📖DNA Damage Repair Mechanisms Across Neurodegenerative Diseas67%

related📖DNA Damage Response Impairment Pathway67%

related📖DNA Damage Response in 4R-Tauopathies67%

related📖DNA Damage Response in Alzheimer's Disease67%

related📖DNA Damage Response in Corticobasal Syndrome67%

related📖DNA Damage Response and Repair in Neurodegeneration67%

related📖DNA Damage Response in Neurons67%

related📖DNA Damage Response in Parkinson's Disease67%

related📖DNA Damage Response in Neurodegeneration67%

related📖DNA Methylation in Neurodegeneration67%

related📖DNA Repair Mechanisms in Neurodegeneration67%

related📖DNA Sensing Pathways in Neurodegeneration67%

related📖DNA Damage and Repair Dysfunction in PSP67%

related📖DNA Ligase III Protein67%

related📖DNA Ligase IV Protein67%

related📖DNA-PKcs (PRKDC) Protein67%

related📖DNA Damage Repair Therapy for Neurodegeneration67%

related📖DNA Repair Therapy for Neurodegeneration67%

related📖Mitochondria63%

related📖Mitochondria-Lysosome Contact Site Dysfunction in Parkinson&63%

related📖Mitochondria-Lysosome Contact Site (MLCS) Dysfunction Hypoth63%

related📖Mitochondria-Lysosome Contact Sites Dysfunction in Parkinson63%

related📖Mitochondria-Lysosome Contact Site Dysfunction in Parkinson&63%

related📖Mitochondria-Lysosome Contact Sites (MLCS) in Neurodegenerat63%

related📖Mitochondria in Neurodegeneration63%

related📖Mitochondria-Lysosome Contact Sites in Parkinson's Dise63%

related📖NAMPT Gene62%

mentions📖Cell-Free DNA Biomarkers in Neurodegeneration60%

mentions📖Alzheimer's Disease DNA Damage Repair and Chromatin Rem60%

mentions📖Parkinson's Disease DNA Damage Repair Therapeutic Compa60%

mentions📖CBS DNA Damage Response Mechanisms60%

mentions📖cGAS-STING Cytosolic DNA Sensing Pathway in Neurodegeneratio60%

mentions📖Huntington's Disease Somatic CAG Expansion and DNA Repa60%

mentions📖Mitochondrial DNA Replication60%

mentions📖TDP-43 DNA Repair Mechanism in ALS and Dementia60%

mentions📖TAR DNA-Binding Protein 43 (TDP-43)60%

mentions📖mechanisms60%

related📖NAMPT Gene56%

related📖Cell-Free DNA Biomarkers in Neurodegeneration54%

related📖Alzheimer's Disease DNA Damage Repair and Chromatin Rem54%

related📖Parkinson's Disease DNA Damage Repair Therapeutic Compa54%

related📖CBS DNA Damage Response Mechanisms54%

related📖cGAS-STING Cytosolic DNA Sensing Pathway in Neurodegeneratio54%

related📖Huntington's Disease Somatic CAG Expansion and DNA Repa54%

related📖Mitochondrial DNA Replication54%

related📖TDP-43 DNA Repair Mechanism in ALS and Dementia54%

related📖TAR DNA-Binding Protein 43 (TDP-43)54%

related📖mechanisms54%

related📖ai-tool-alibaba-tongyi-qianwen-bio52%

related📖ai-tool-bioframe52%

related📖ai-tool-biorxiv-literature-agent52%

related📖ai-tool-nucleus-dnastack52%

related📖ai-tool-openai-codex-biology52%

related📖ai-tools-inference-bio52%

related📖Neurodegeneration52%

mentions📖Beta-Propeller Protein-Associated Neurodegeneration (BPAN)50%

mentions📖China Neurodegeneration Epidemiology50%

mentions📖DALY Methodology — Neurodegeneration50%

mentions📖Disease Progression & Staging in Neurodegeneration50%

mentions📖Economic Burden — Neurodegeneration50%

mentions📖European Neurodegeneration Epidemiology50%

mentions📖Familial vs Sporadic Neurodegeneration Comparison50%

mentions📖Global Neurodegeneration Epidemiology50%

mentions📖India Neurodegeneration Epidemiology50%

mentions📖Japan Neurodegeneration Epidemiology50%

mentions📖Manganese-Related Neurodegeneration (Manganism)50%

mentions📖mitochondrial-dysfunction-neurodegeneration-comparison50%

mentions📖Mitochondrial Diseases and Neurodegeneration Comparison Matr50%

mentions📖Mitochondrial Membrane Protein-Associated Neurodegeneration 50%

mentions📖Neurodegeneration with Brain Iron Accumulation (NBIA)50%

mentions📖Neurodegeneration50%

mentions📖Potential Impact Measures — Neurodegeneration50%

mentions📖Pantothenate Kinase-Associated Neurodegeneration (PKAN)50%

mentions📖PLA2G6-Associated Neurodegeneration (PLAN)50%

mentions📖Sleep Disorders in Neurodegeneration50%

mentions📖US Neurodegeneration Epidemiology50%

related📖AMPK (AMP-Activated Protein Kinase)40%

related📖SIRT6 Gene40%

related📖AMPK Agonist Therapy for Neurodegeneration40%

related📖TET2 Gene40%

related📖HDAC Inhibitors for Neurodegeneration — Investment Landscape40%

related📖SIRT3 - Sirtuin 340%

related📖entities-sirt140%

related📖app40%

related📖SIRT1 Gene40%

related📖APP Gene Dosage Reduction Therapy for Down Syndrome40%

related📖APP Protein40%

related📖ATG5 — Autophagy Related 540%

related📖ATG5 Protein40%

related📖MDM2 Gene40%

related📖ATG7 Gene40%

related📖atg740%

related📖First-in-Human 4R Tau Ligand Study in PSP (NCT07348276)40%

related📖Tau Protein40%

related📖BDNF Gene40%

related📖Brain-Derived Neurotrophic Factor (BDNF)40%

related📖SYN1 Gene40%

related📖BMAL1 (ARNTL) Gene40%

related📖BRD4 (Bromodomain-Containing Protein 4)40%

related📖HDAC3 Gene40%

related📖PGC1A Gene40%

related📖cd3340%

related📖CD33 Modulation Therapy for Neurodegeneration40%

related📖CD33 (Siglec-3)40%

related📖CDK5 Gene40%

related📖cdk540%

related📖CSF1R — Colony Stimulating Factor 1 Receptor40%

related📖CSF1R Protein (Colony Stimulating Factor 1 Receptor)40%

related📖DLG4 Gene - PSD-9540%

related📖GRIN2B — NMDA Receptor Subunit 2B40%

related📖PARP1 Gene40%

related📖PARP1 (Poly(ADP-Ribose) Polymerase 1)40%

related📖entities-gdnf40%

related📖GDNF — Glial Cell Line-Derived Neurotrophic Factor40%

related📖Glial Cell Derived Neurotrophic Factor (GDNF)40%

related📖Lysosomal Associated Membrane Protein 1 (LAMP1)40%

related📖LAMP1 Protein40%

related📖entities-ngf40%

related📖NGF Gene40%

related📖sTREM2 (Soluble TREM2) - Biomarker40%

related📖TREM2 Protein (Triggering Receptor Expressed on Myeloid Cell40%

related📖TREM2 — Triggering Receptor Expressed on Myeloid Cells 240%

related📖trem2-alpha-synuclein-clearance-parkinsons40%

related📖TREM2 Mechanism Hub40%

related📖TREM2 Protein40%

related📖entities-psen140%

related📖PSEN1 — Presenilin 140%

related📖PSEN1 Protein (Presenilin-1)40%