🧫

Electroacupuncture ST37 treatment for DSS-induced colitis in mice

active
experiment Created: 2026-04-11T00:47:02 By: experiment_extractor Quality: 95% ✓ SciDEX ID: experiment-exp-36adfa0c-75e6-4898-b4fd-a
🧫 Experiment Protocol Animal Modelproposed
Related Entities
CHAT, CHRNA7
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-11T00:47:02.182451'}
p_value<0.05
protocolMice received 2.5% DSS solution for 7 days to induce colitis, followed by electroacupuncture treatment at ST37 acupoint. Assessment included body weight monitoring, colon length measurement, H&E stain
effect_sizeNone
sample_sizeNone
source_pmid41847427
extracted_at2026-04-10T17:47:02.179682
_schema_version1
experiment_typeanimal_model
success_criteriaSignificant reduction in body weight loss, decreased colon tissue damage, reduced pro-inflammatory cytokine levels, increased ChAT neuron activation, and restored α7nAChR expression
expected_outcomesEA treatment was expected to and did reduce colitis severity, decrease pro-inflammatory cytokines, activate ChAT-positive neurons in DMV, restore α7nAChR levels, and increase vagal efferent activity t
statistical_methodsNone
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
74
Outgoing
20
0 supporting 0 contradicting 0 neutral
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