🧫

TREK-1 effects on spontaneous OHT in rats using telemetry

experiment Created: 2026-04-10 03:37:12 By: experiment_extractor Quality: 80% ✓ SciDEX ID: experiment-exp-3762f9a4-78dd-46b0-bd08-8
🧫 Experiment Protocol Animal Model
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Related Entities
KCNK2 (TREK-1)
Metadata
experiment_typeanimal_model
protocolContinuous IOP telemetry monitoring with ML-402 treatment
expected_outcomesML-402 would reduce spontaneously elevated IOP
success_criteriaSignificant IOP reduction detected by telemetry
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-09T20:37:01.794569
source_pmid41268978
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T03:37:12.626344'}
🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

Linked Artifacts (8)
derives_from📄Mechano- and Glucocorticoid-Sensitive TREK-1 Channels Regula100%
related🧫TREK-1 regulation of conventional outflow facility in mouse 100%
related🧫DEX effects on TREK-1 currents in human primary TM cells100%
related🧫TREK-1 localization in trabecular meshwork by immunohistoche100%
related🧫TREK-1 effects on IOP in DEX-induced mouse OHT model100%
related🧫DEX effects on K2P channel transcriptome in mouse TM cells100%
mentions📖TREK-1 Protein70%
related📖TREK-1 Protein63%