🧫

DEX effects on K2P channel transcriptome in mouse TM cells

experiment Created: 2026-04-10 03:37:12 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-b63db77f-7772-437a-a677-a
🧫 Experiment Protocol Gene Expression
🧫 View Full Experiment Page →
Related Entities
KCNK2 (TREK-1)
Metadata
experiment_typegene_expression
protocolReal-time PCR analysis of K2P, TRPV, Piezo channel, ECM, and fibrotic marker genes after DEX treatment
expected_outcomesDEX would alter expression of mechanosensitive channels and fibrotic markers
success_criteriaSignificant changes in mRNA expression levels detected by qPCR
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-09T20:37:01.794554
source_pmid41268978
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T03:37:01.797114'}
🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

Linked Artifacts (16)
derives_from📄Mechano- and Glucocorticoid-Sensitive TREK-1 Channels Regula100%
related🧫TREK-1 regulation of conventional outflow facility in mouse 100%
related🧫DEX effects on TREK-1 currents in human primary TM cells100%
related🧫TREK-1 effects on spontaneous OHT in rats using telemetry100%
related🧫TREK-1 localization in trabecular meshwork by immunohistoche100%
related🧫TREK-1 effects on IOP in DEX-induced mouse OHT model100%
mentions📖TREK-1 Protein70%
mentions📖TRPC1 Gene70%
mentions📖TRPC1 Protein70%
mentions📖TRPV4 Gene70%
mentions📖TRPV4 Protein70%
related📖TREK-1 Protein63%
related📖TRPC1 Gene63%
related📖TRPC1 Protein63%
related📖TRPV4 Gene63%
related📖TRPV4 Protein63%