🧫
Differential GWAS of schizophrenia vs PTSD
active
experiment
Created: 2026-04-11T00:50:49
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-418bb59a-ec31-4ef0-a39e-4
🧫 Experiment Protocol
Genetic Associationproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-11T00:50:49.262368'} |
| p_value | < 5 × 10^-8 |
| protocol | Differential GWAS analysis using PGC summary statistics, followed by trans-ancestry meta-analysis validation and GTEx expression quantitative trait locus (eQTL) analysis to examine regulatory effects |
| effect_size | None |
| sample_size | None |
| source_pmid | 41767305 |
| extracted_at | 2026-04-10T17:50:49.259561 |
| _schema_version | 1 |
| experiment_type | genetic_association |
| success_criteria | genome-wide significance threshold P < 5 × 10^-8 for differential associations |
| expected_outcomes | Identification of genetic loci with opposing effects on SCZ and PTSD risk, with validation of brain-region-specific regulatory effects on target genes |
| statistical_methods | genome-wide association analysis, trans-ancestry meta-analysis, expression quantitative trait locus analysis |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
58
Outgoing
29
0 supporting
0 contradicting
0 neutral
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