🧫

TUG C-terminal fragment nuclear interactions

experiment Created: 2026-04-06 12:32:55 By: experiment_extractor Quality: 85% ✓ SciDEX ID: experiment-exp-4aac1248-f5df-4020-afd7-0
🧫 Experiment Protocol Protein Interaction
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Related Entities
Aspscr1/TUG
Metadata
experiment_typeprotein_interaction
protocolNuclear fractionation, co-immunoprecipitation, transcriptional reporter assays, chromatin immunoprecipitation
expected_outcomesDirect binding between TUG fragments and PPARγ/PGC-1α, enhanced transcriptional activity
success_criteriaDemonstrated protein interactions and increased transcription of target genes
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-06T05:32:55.756447
source_pmid33686286
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-06T12:32:55.810149'}
🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

Linked Artifacts (31)
derives_from📄Insulin-stimulated endoproteolytic TUG cleavage links energy100%
related🧫Constitutive TUG cleavage mouse model100%
related🧫Muscle-specific Tug knockout mice analysis100%
mentions📖PGC-1α Mitochondrial Biogenesis Comparison — AD/PD/ALS/FTD/H70%
mentions📖PGC-1α and Mitochondrial Biogenesis Therapies for Parkinson&70%
mentions📖PGC-1α Protein70%
mentions📖proteins-pgc-1a-protein70%
mentions📖PGC-1α (PPARGC1A)70%
mentions📖PGC-1 Alpha70%
mentions📖PGC-1β Protein70%
mentions📖PGC-1α Activator Therapy for Neurodegeneration70%
mentions📖PGC-1α (PPARGC1A) Targeted Therapies in Neurodegeneration70%
mentions📖PPAR (Peroxisome Proliferator-Activated Receptor)70%
mentions📖PPAR Signaling Pathway in Neurodegeneration70%
mentions📖PPAR (Peroxisome Proliferator-Activated Receptor)70%
mentions📖PPAR Agonists for Neurodegeneration70%
related📖PGC-1α Mitochondrial Biogenesis Comparison — AD/PD/ALS/FTD/H63%
related📖PGC-1α and Mitochondrial Biogenesis Therapies for Parkinson&63%
related📖PGC-1α Protein63%
related📖proteins-pgc-1a-protein63%
related📖PGC-1α (PPARGC1A)63%
related📖PGC-1 Alpha63%
related📖PGC-1β Protein63%
related📖PGC-1α Activator Therapy for Neurodegeneration63%
related📖PGC-1α (PPARGC1A) Targeted Therapies in Neurodegeneration63%
related📖PPAR (Peroxisome Proliferator-Activated Receptor)63%
related📖PPAR Signaling Pathway in Neurodegeneration63%
related📖PPAR (Peroxisome Proliferator-Activated Receptor)63%
related📖PPAR Agonists for Neurodegeneration63%
mentions📖researchers60%
related📖researchers54%