🧫

P2RY12-MTOR pathway interaction in VSMCs

experiment Created: 2026-04-04 05:26:15 By: experiment_extractor Quality: 85% ✓ SciDEX ID: experiment-exp-764173ae-f63f-452f-b821-2
🧫 Experiment Protocol Cell Biology
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Related Entities
P2RY12, MTOR
Metadata
experiment_typecell_biology
protocolMTOR inhibition with rapamycin, genetic MTOR knockdown, cholesterol efflux assays, autophagy marker analysis
expected_outcomesMTOR inhibition would reverse P2RY12-mediated effects on cholesterol efflux and autophagy
success_criteriaRestoration of cholesterol efflux and autophagy when MTOR is blocked
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-03T22:26:15.619136
source_pmid32160082
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-04T05:26:15.811936'}
🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

Linked Artifacts (150)
derives_from📄The P2RY12 receptor promotes VSMC-derived foam cell formatio100%
experiment_target📖P2RY12100%
mentions📖MTOR100%
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mentions📖MTOR Protein80%
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related📖MTOR Protein72%
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💬 Discussion