🧫
Tet2 modulation in Aβ42-injured mouse hippocampal neurons
active
experiment
Created: 2026-04-10T22:33:00
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-844b1c39-b8a4-4082-b3d4-9
🧫 Experiment Protocol
Cell Biologyproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:33:00.183857'} |
| p_value | None |
| protocol | Primary hippocampal neurons treated with Aβ42 oligomers, followed by transfection with recombinant plasmids for Tet2 knockdown or overexpression |
| effect_size | None |
| sample_size | None |
| source_pmid | 33165916 |
| extracted_at | 2026-04-10T15:33:00.181011 |
| _schema_version | 1 |
| experiment_type | cell_biology |
| success_criteria | Neuronal viability and morphological integrity under amyloid stress conditions |
| expected_outcomes | Tet2 overexpression would protect against Aβ42 toxicity while Tet2 knockdown would worsen neuronal damage |
| statistical_methods | None |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
68
Outgoing
22
0 supporting
0 contradicting
0 neutral
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