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Cx43 knockdown effects on mitochondrial transfer

experiment Created: 2026-04-10 14:35:39 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-8659e7c7-cdf8-4783-af40-9
🧫 Experiment Protocol Gene Expression
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Related Entities
GJA1
Metadata
experiment_typegene_expression
protocolsiRNA-mediated knockdown of Cx43 in MSCs, co-culture with chondrocytes, flow cytometry quantification of mitochondrial transfer
expected_outcomesDecreased mitochondrial transfer with reduced Cx43 expression
success_criteriaSignificant reduction in mitochondrial transfer compared to control
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-10T07:35:39.807171
source_pmid39390589
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T14:35:39.964806'}
🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

Linked Artifacts (15)
derives_from📄Connexin 43 regulates intercellular mitochondrial transfer f100%
related🧫Confocal imaging of MSC-chondrocyte interactions during mito100%
related🧫Cx43 and GJA1-20k overexpression effects on mitochondrial tr100%
related🧪CX43 hemichannel engineering enables size-selective mitochon100%
related🧪Astrocytic Connexin-43 Upregulation Enhances Neuroprotective100%
related🧪Astroglial Gap Junction Coordination via Connexin-43 Phospho100%
mentions📖GJA180%
mentions📖GJA1 Protein80%
related📖GJA172%
related📖GJA1 Protein72%
mentions📖Mitochondria60%
related🧪CX43 hemichannel engineering enables size-selective mitochon60%
related🧪Astrocytic Connexin-43 Upregulation Enhances Neuroprotective60%
related🧪Astroglial Gap Junction Coordination via Connexin-43 Phospho60%
related📖Mitochondria54%