🧫
Periodontitis-induced colonic inflammation in mice
active
experiment
Created: 2026-04-10T22:49:24
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-96ca29f6-fdad-46e2-92e2-2
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:49:24.644409'} |
| p_value | None |
| protocol | Ligature-induced periodontitis in mice, followed by micro-CT analysis, histological evaluation, qPCR, immunostaining, ELISA, and GC-MS/MS analysis of colonic contents |
| effect_size | None |
| sample_size | None |
| source_pmid | 41816355 |
| extracted_at | 2026-04-10T15:49:24.641392 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Significant changes in GPR109A expression, tight junction protein localization, and inflammatory markers |
| expected_outcomes | Periodontitis would downregulate GPR109A expression and disrupt intestinal barrier function |
| statistical_methods | None |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
40%
Debates
0
Incoming
8
Outgoing
5
0 supporting
0 contradicting
0 neutral
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