🧫

Unilateral anterior crossbite (UAC) model of TMJOA in rats

active
experiment Created: 2026-04-10T22:49:51 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-d6c48a0b-9631-49bc-a83f-5
🧫 Experiment Protocol Animal Modelproposed
Related Entities
Cx43
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:49:51.844836'}
p_valueNone
protocolInduction of unilateral anterior crossbite in rats followed by assessment of TMJ degeneration, Cx43 expression analysis, and Wnt/β-catenin pathway activation in condylar cartilage
effect_sizeNone
sample_sizeNone
source_pmid41757775
extracted_at2026-04-10T15:49:51.837926
_schema_version1
experiment_typeanimal_model
success_criteriaDemonstration of TMJ degeneration, upregulated Cx43 expression, and activated Wnt/β-catenin signaling
expected_outcomesUAC would induce OA-like changes with increased Cx43 expression and Wnt pathway activation
statistical_methodsNone
📊 Evidence Profile
Evidence Balance
+0%
Certainty
40%
Debates
0
Incoming
8
Outgoing
4
0 supporting 0 contradicting 0 neutral
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