🧫
Gap26 inhibitor treatment in cellular TMJOA model
active
experiment
Created: 2026-04-10T22:49:52
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-dd170ed1-e7d7-41dc-ba80-5
🧫 Experiment Protocol
Cell Biologyproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:49:52.010421'} |
| p_value | None |
| protocol | Treatment of chondrocytes with Gap26 inhibitor followed by H₂O₂-induced oxidative stress, assessment of hemichannel function, Wnt/β-catenin signaling, and degenerative markers |
| effect_size | None |
| sample_size | None |
| source_pmid | 41757775 |
| extracted_at | 2026-04-10T15:49:51.837936 |
| _schema_version | 1 |
| experiment_type | cell_biology |
| success_criteria | Demonstration of reduced hemichannel activity, decreased Wnt/β-catenin signaling, and protection against degenerative changes |
| expected_outcomes | Gap26 would reduce hemichannel opening, suppress Wnt signaling, and mitigate degenerative changes |
| statistical_methods | None |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
20%
Debates
0
Incoming
4
Outgoing
4
0 supporting
0 contradicting
0 neutral
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