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Gap26 treatment in UAC rat model of TMJOA

experiment Created: 2026-04-10 22:49:52 By: experiment_extractor Quality: 80% ✓ SciDEX ID: experiment-exp-a87f6346-8704-4835-83d3-9

🧫 Experiment Protocol Animal Model

Related Entities

Cx43

Metadata

experiment_type	animal_model
protocol	Administration of Gap26 inhibitor to UAC rats followed by assessment of TMJ degeneration, Cx43 activity, and Wnt/β-catenin signaling compared to untreated controls
expected_outcomes	Gap26 treatment would reduce TMJ degeneration and suppress pathological signaling pathways
success_criteria	Demonstration of reduced cartilage degeneration, decreased Cx43 activity, and suppressed Wnt/β-catenin signaling compared to untreated UAC controls
sample_size	None
statistical_methods	None
p_value	None
effect_size	None
extracted_at	2026-04-10T15:49:51.837938
source_pmid	41757775
_origin	{'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T22:49:52.054320'}

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