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Microglial SIRPα expression in human Alzheimer's disease tissue

experiment Created: 2026-04-10 23:10:58 By: experiment_extractor Quality: 80% ✓ SciDEX ID: experiment-exp-e04a8a6c-603c-40c6-af10-a
🧫 Experiment Protocol Neuropathology
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Related Entities
SIRPα
Metadata
experiment_typeneuropathology
protocolAnalysis of microglial SIRPα expression in human brain tissue samples from Alzheimer's disease patients at different disease stages
expected_outcomesDeclining microglial SIRPα expression with Alzheimer's disease progression
success_criteriaSignificant correlation between reduced SIRPα expression and disease progression
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-10T16:10:58.597425
source_pmid33795678
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T23:10:58.673083'}
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Linked Artifacts (37)
related🧫SIRPα modulation in mouse models of Alzheimer's disease100%
related🧫Microglia-specific SIRPα deletion in conditional knockout mi100%
mentions📖Agitation in Alzheimer's Disease60%
mentions📖Alzheimer's Disease60%
mentions📖Alzheimer's Disease Genetic Variants60%
mentions📖Alzheimer's Disease vs Parkinson's Disease Compari60%
mentions📖APP Mutations in Alzheimer's Disease60%
mentions📖DLB, Parkinson's Disease, and Alzheimer's Disease:60%
mentions📖Early-Onset Alzheimer's Disease (EOAD)60%
mentions📖Investment Landscape: Alzheimer's Disease60%
mentions📖Preclinical Alzheimer's Disease60%
mentions📖Prodromal Alzheimer's Disease60%
mentions📖PSEN1 Mutations in Alzheimer's Disease60%
mentions📖PSEN2 Mutations in Alzheimer's Disease60%
mentions📖Sporadic vs Familial Alzheimer's Disease: Comprehensive60%
mentions📖TREM2 Variants in Alzheimer's Disease60%
mentions📖Microglia60%
mentions📖Microglia60%
mentions📖researchers60%
related📖Alzheimer's Disease60%
related📖Agitation in Alzheimer's Disease54%
related📖Alzheimer's Disease54%
related📖Alzheimer's Disease Genetic Variants54%
related📖Alzheimer's Disease vs Parkinson's Disease Compari54%
related📖APP Mutations in Alzheimer's Disease54%
related📖DLB, Parkinson's Disease, and Alzheimer's Disease:54%
related📖Early-Onset Alzheimer's Disease (EOAD)54%
related📖Investment Landscape: Alzheimer's Disease54%
related📖Preclinical Alzheimer's Disease54%
related📖Prodromal Alzheimer's Disease54%
related📖PSEN1 Mutations in Alzheimer's Disease54%
related📖PSEN2 Mutations in Alzheimer's Disease54%
related📖Sporadic vs Familial Alzheimer's Disease: Comprehensive54%
related📖TREM2 Variants in Alzheimer's Disease54%
related📖Microglia54%
related📖Microglia54%
related📖researchers54%