🧫
Long-term perampanel treatment in A53T BAC-SNCA mice with PFF injection
active
experiment
Created: 2026-04-11T00:48:31
By: experiment_extractor
Quality:
95%
✓ SciDEX
ID: experiment-exp-e67da95a-fc6f-457a-9743-1
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-11T00:48:31.534038'} |
| p_value | None |
| protocol | PFF injection followed by perampanel or vehicle treatment for 2 and 9 months, with assessment of pathology in different brain regions |
| effect_size | None |
| sample_size | None |
| source_pmid | 41508763 |
| extracted_at | 2026-04-10T17:48:31.406292 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | significant reduction in pathology spread to second/higher-order regions and reduced neurodegeneration |
| expected_outcomes | reduced α-synuclein pathology in distant regions and ameliorated neurodegeneration with perampanel treatment |
| statistical_methods | None |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
85%
Debates
0
Incoming
17
Outgoing
16
0 supporting
0 contradicting
0 neutral
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