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How does ITGAM interact with [APOE](/genes/apoe)-[TREM2](/genes/trem2) programs across disease stages?

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open question Created: 2026-04-25T20:25:48 By: backfill_open_questions Quality: 50% ✓ SciDEX ID: open_question-47cc887f-9ec6-4e81-b6c2-c9

Open Question open Wiki: genes-itgam

How does ITGAM interact with [APOE](/genes/apoe)-[TREM2](/genes/trem2) programs across disease stages?

Importance Elo

1500

Field Rank

Rank #865 in genes

Tractability

0.50

Potential Impact

0.50

Evidence Summary

Extracted from wiki page genes-itgam

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▸Metadata

status	open
_origin	{'url': None, 'type': 'internal', 'tracked_at': '2026-04-26T03:25:48.416072'}
field_tag	genes
source_id	genes-itgam
sub_field	itgam
source_kind	wiki
question_hash	723e0fbc7e40bb3d2aa72f5bb386cf620948140f7a1a9fc749c5ae6eb6d3b0ec
question_text	How does ITGAM interact with [APOE](/genes/apoe)-[TREM2](/genes/trem2) programs across disease stages?
importance_elo	1500
_schema_version	1
evidence_summary	Extracted from wiki page genes-itgam
tractability_score	0.5
potential_impact_score	0.5

📊 Evidence Profile

Evidence Balance

+0%

Certainty

0%

Debates

0

Incoming

0

Outgoing

1

0 supporting 0 contradicting 0 neutral

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