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SRPK1 is a poor prognostic indicator and a novel potential therapeutic target for human colorectal cancer.
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ID: paper-30214242
📄 Paper Details
SRPK1 is a poor prognostic indicator and a novel potential therapeutic target for human colorectal cancer.
["Yi N", "Xiao M", "Jiang F", "Liu Z", "Ni W", "Lu C", "Ni R", "Chen W"]
Abstract
BACKGROUND: Serine/arginine protein kinase 1 (SRPK1) is a protein kinase that belongs to the serine/arginine-rich domain family of splicing factors which are essential for splice-site selection, especially the modulation for RNA metabolism, localization, and translation. High expression of SRPK1 has been found in numerous human cancers, but its mechanism in colorectal cancer (CRC) is still rarely reported. PURPOSE: To investigate the expression of SRPK1 in CRC tissues and cells and determine its...
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