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Fig. 3: Distinct transcriptional signature between CLP- and GSK484-treated hippocampus. ...
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Created: 2026-04-16T11:31:44
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ID: paper-fig-40102948-3
Fig. 3Figure 3
Distinct transcriptional signature between CLP- and GSK484-treated hippocampus. A A vulcano plot was depicted with p < 0.05 of all 705 detected genes from RNA-Seq dataset. Differential expression genes (DEGs) were colored with blue and red, regarding to 163 down-regulated and 542 up-regulated genes, respectively. B Bar plot of GO enrichment analysis; (BP) biological process, (CC) cellular components, (MF) molecular function. C Bubble plot of KEGG pathway analysis. D Cytoscape was used to visualize the PPI network generated by String. E The top 10 hub genes were obtained using the CytoHubba plug-in in Cytoscape. F The top 1 modules are presented based on MCODE scores in descending order. DEGs: Differential expression genes; BP: biological process; CC: cellular components; MF: molecular function; CLP: Cecal Ligation and Puncture; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes
▸Metadata
| doi | |
| pmcid | PMC11917101 |
| _origin | {'url': 'https://www.ebi.ac.uk/europepmc/articles/PMC11917101/bin/12974_2025_3395_Fig3_HTML.jpg', 'type': 'external', 'tracked_at': '2026-04-16T11:31:44.197085'} |
| caption | Distinct transcriptional signature between CLP- and GSK484-treated hippocampus. A A vulcano plot was depicted with p < 0.05 of all 705 detected genes from RNA-Seq dataset. Differential expression |
| paper_id | 40102948 |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC11917101/bin/12974_2025_3395_Fig3_HTML.jpg |
| image_path | |
| description | |
| figure_label | Fig. 3 |
| figure_number | 3 |
| _schema_version | 1 |
| source_strategy | pmc_api |
| entities_mentioned |
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