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Figure 2 — Targeting the D Series Resolvin Receptor System for the Treatment of Osteoarthri
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Created: 2026-04-21T18:29:40
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Figure 2Figure 2
Expression of resolvin receptors ALX and ChemR23 in rat osteoarthritis (OA) joint tissue. A and B, Significant weight‐bearing asymmetry ( A ) and decreased ipsilateral paw withdrawal thresholds ( B ) following intraarticular injection of monosodium iodoacetate (MIA) into the knee joints (MIA‐treated rats) compared with saline‐treated control rats (n = 8 per group). Values are the mean ± SEM. ∗∗∗∗ = P < 0.0001 versus control, by two‐way analysis of variance with Bonferroni's post hoc test. C and D, Decreased synovial expression of ChemR23 in MIA‐treated rats compared with saline‐treated control rats on day 14 ( C ) and day 35 ( D ). E and F, Comparable expression of ALX in the synovium of MIA‐treated rats and saline‐treated rats on day 14 ( E ) and day 35 ( F ) (n = 7–8 per group). Bars in C – F show the mean ± SEM. ∗ = P < 0.05; ∗∗ = P < 0.01 by unpaired t ‐test.
▸Metadata
| pmid | paper-796580b4c70c |
| caption | Expression of resolvin receptors ALX and ChemR23 in rat osteoarthritis (OA) joint tissue. A and B, Significant weight‐bearing asymmetry ( A ) and decreased ipsilateral paw withdrawal thresholds ( |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC5763389/bin/ART-69-996-g002.jpg |
| paper_title | Targeting the D Series Resolvin Receptor System for the Treatment of Osteoarthritis Pain. |
| figure_label | Figure 2 |
| figure_number | 2 |
| _schema_version | 1 |
| source_strategy | pmc_api |
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