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SHARPIN — SHANK Associated RH Domain Interactor

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-sharpin
Related Entities
SHARPIN
Metadata
sluggenes-sharpin
entity_typegene
kg_node_idSHARPIN
Linked Artifacts (54)
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mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%
mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%
mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%
mentions🧪APOE Isoform Expression Across Glial Subtypes50%
mentions🧪Senescence-Associated Myelin Lipid Remodeling50%
mentions🧪Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu50%
mentions🧪Low Complexity Domain Cross-Linking Inhibition50%
mentions🧪Glycine-Rich Domain Competitive Inhibition50%
mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%
mentions🧪Competitive APOE4 Domain Stabilization Peptides50%
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related🔬The disease-associated microglia (DAM) phenotype involves TR50%
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mentions🔬The disease-associated microglia (DAM) phenotype involves TR40%
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mentions🔬APOE4 differs from APOE3 by C112R causing domain interaction40%
mentions🔬Analyze circuit-level changes in neurodegeneration using All40%
related🧪Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu40%
related🧪Low Complexity Domain Cross-Linking Inhibition40%
related🧪Glycine-Rich Domain Competitive Inhibition40%
related🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction40%
related🧪Senescence-Associated Myelin Lipid Remodeling40%
related🧪Competitive APOE4 Domain Stabilization Peptides40%