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Tokyo NeuroInnovation

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institutions-tokyo-neuroinnovation

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slug	institutions-tokyo-neuroinnovation
entity_type	institution
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Linked Artifacts (45)

mentions🧪APOE Isoform Conversion Therapy50%

mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%

mentions🧪APOE4-Selective Lipid Nanoemulsion Therapy50%

mentions🧪APOE Isoform Expression Across Glial Subtypes50%

related🔬What are the mechanisms underlying selective vulnerability o50%

related🔬What are the mechanisms underlying blood-brain barrier trans50%

related🔬What are the mechanisms underlying apoe4 structural biology 50%

related🔬Investigate how lipid raft composition (cholesterol metaboli50%

related🔬Investigate prion-like spreading of tau pathology through co50%

related🔬What are the mechanisms underlying selective vulnerability o50%

related🔬What are the mechanisms underlying blood-brain barrier trans50%

related🔬What are the mechanisms underlying apoe4 structural biology 50%

related🔬Investigate how lipid raft composition (cholesterol metaboli50%

related🔬Investigate prion-like spreading of tau pathology through co50%

mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer45%

mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones45%

mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction45%

mentions🧪Competitive APOE4 Domain Stabilization Peptides45%

mentions🧪Membrane Cholesterol Gradient Modulators45%

mentions🧪LRP1-Dependent Tau Uptake Disruption45%

mentions🧪Circadian-Synchronized LRP1 Pathway Activation45%

mentions🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides45%

mentions🧪Synthetic Biology BBB Endothelial Cell Reprogramming45%

mentions🧪Magnetosonic-Triggered Transferrin Receptor Clustering45%

mentions📖Alzheimer's Disease40%

mentions📖Neurodegeneration40%

mentions📖Parkinson's Disease40%

mentions📖ENDOG40%

mentions📖Parkin40%

related🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer40%

related🧪APOE4 Allosteric Rescue via Small Molecule Chaperones40%

related🧪LRP1-Dependent Tau Uptake Disruption40%

related🧪Circadian-Synchronized LRP1 Pathway Activation40%

related🧪Synthetic Biology BBB Endothelial Cell Reprogramming40%

related🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction40%

related🧪Membrane Cholesterol Gradient Modulators40%

related🧪Magnetosonic-Triggered Transferrin Receptor Clustering40%

related🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides40%

related🧪Competitive APOE4 Domain Stabilization Peptides40%

related🧪LRP1-Dependent Tau Uptake Disruption40%

related🧪Extracellular Vesicle Biogenesis Modulation40%

related🧪TREM2-mediated microglial tau clearance enhancement40%

related🧪Perforant Path Presynaptic Terminal Protection Strategy40%

related🧪Reelin-Mediated Cytoskeletal Stabilization Protocol40%

related🧪Tau-Independent Microtubule Stabilization via MAP6 Enhanceme40%