🧫

Activity-dependent PGC-1α transcriptional program analysis

active
experiment Created: 2026-04-06T12:34:10 By: experiment_extractor Quality: 80% ✓ SciDEX ID: experiment-exp-124091e6-5ba4-459c-acdf-e
🧫 Experiment Protocol Gene Expressionproposed
Related Entities
PGC-1α, ERRγ, Mef2c
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-06T12:34:10.667779'}
p_valueNone
protocolActivity manipulation followed by transcriptomic analysis, chromatin immunoprecipitation, and gene expression profiling
effect_sizeNone
sample_sizeNone
source_pmid40669459
extracted_at2026-04-06T05:34:10.639160
_schema_version1
experiment_typegene_expression
success_criteriaDemonstration of activity-dependent activation of PGC-1α transcriptional complex and downstream gene expression changes
expected_outcomesNeural activity would trigger PGC-1α-mediated transcriptional changes leading to PV+ interneuron maturation
statistical_methodsNone
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
47
Outgoing
44
0 supporting 0 contradicting 0 neutral
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