🧫
NAD depletion effects on monocyte/macrophage differentiation
active
experiment
Created: 2026-04-10T14:44:04
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-668ff0ed-593d-4597-a9d6-f
🧫 Experiment Protocol
Cell Biologyproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T14:44:04.713884'} |
| p_value | None |
| protocol | Isolation of primary monocytes/macrophages, FK866 treatment, assessment of differentiation markers and cytokine profiles |
| effect_size | None |
| sample_size | None |
| source_pmid | 28877980 |
| extracted_at | 2026-04-10T07:44:04.645410 |
| _schema_version | 1 |
| experiment_type | cell_biology |
| success_criteria | Significant changes in polarization markers (CD86, CD38, MHC-II, IL-6 reduction; CD206, Egr2, IL-10 increase) |
| expected_outcomes | Altered macrophage polarization with reduced pro-inflammatory and increased anti-inflammatory markers |
| statistical_methods | None |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
32
Outgoing
24
0 supporting
0 contradicting
0 neutral
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