🧫

GTEx brain tissue expression analysis of MAPT/CRHR1 locus

active
experiment Created: 2026-04-11T00:50:49 By: experiment_extractor Quality: 85% ✓ SciDEX ID: experiment-exp-b4197a48-56d0-4213-b0b2-0
🧫 Experiment Protocol Gene Expressionproposed
Related Entities
MAPT, CRHR1
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-11T00:50:49.295427'}
p_valueNone
protocolGTEx expression quantitative trait locus analysis examining regulatory effects of rs62062288 on MAPT and CRHR1 expression across multiple brain regions including caudate basal ganglia, frontal cortex
effect_sizeNone
sample_sizeNone
source_pmid41767305
extracted_at2026-04-10T17:50:49.259567
_schema_version1
experiment_typegene_expression
success_criteriasignificant eQTL associations in brain tissues
expected_outcomesOpposite regulatory effects on MAPT and CRHR1 expression, with tissue-specific patterns of regulation
statistical_methodsexpression quantitative trait locus analysis
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
46
Outgoing
18
0 supporting 0 contradicting 0 neutral
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