🧫
Bmal1 knockout in mPFC excitatory neurons
active
experiment
Created: 2026-04-11T00:49:32
By: experiment_extractor
Quality:
95%
✓ SciDEX
ID: experiment-exp-c37c2209-0e35-4e18-95d5-5
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-11T00:49:32.250853'} |
| p_value | None |
| protocol | Stereotaxic viral injection for Bmal1 deletion in mPFC CaMK2a+ neurons, sleep monitoring, behavioral testing, molecular analysis |
| effect_size | None |
| sample_size | None |
| source_pmid | 41023421 |
| extracted_at | 2026-04-10T17:49:32.189585 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Complete elimination of SD behavioral and molecular effects in Bmal1 knockout mice |
| expected_outcomes | Disrupted sleep homeostasis and abolished antidepressant response to sleep deprivation |
| statistical_methods | None |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
40%
Debates
0
Incoming
8
Outgoing
10
0 supporting
0 contradicting
0 neutral
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