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Why do VCP mutations cause tissue-specific phenotypes (muscle, bone, brain)?

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open question Created: 2026-04-25T20:28:40 By: backfill_open_questions Quality: 50% ✓ SciDEX ID: open_question-1c6757c8-9aed-4a88-b3a8-e0
Open Question open Wiki: proteins-valosin
Why do VCP mutations cause tissue-specific phenotypes (muscle, bone, brain)?
Importance Elo
1500
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Rank #384 in proteins
Tractability
0.50
Potential Impact
0.50
Evidence Summary
Extracted from wiki page proteins-valosin
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statusopen
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-26T03:28:40.559218'}
field_tagproteins
source_idproteins-valosin
sub_fieldvalosin
source_kindwiki
question_hash7c75b8c2b0a714d4b084e548b1e6031a4ffd4da40bd93fb55e84fb727a7f404a
question_textWhy do VCP mutations cause tissue-specific phenotypes (muscle, bone, brain)?
importance_elo1500
_schema_version1
evidence_summaryExtracted from wiki page proteins-valosin
tractability_score0.5
potential_impact_score0.5
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