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Fig. 10: DAPK1 inhibition ameliorates emotional and cognitive impairments in a mouse mode...
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Fig. 10Figure 10
DAPK1 inhibition ameliorates emotional and cognitive impairments in a mouse model of tauopathy. ( A-B) The Y-maze test was applied to evaluate the short-term memory ability in mice treated with or without C6. The number of NA entry and the percentage of time spent in NA for each group are presented. n = 9–11 mice/group. (C-F) The open field test (OFT) was employed to analyze the anxiety-like behavior in mice treated with or without C6. Representative movement trajectories ( C ) for each group are shown. The blue square indicates the center area in OFT. The total ambulatory distance ( D ), the percentage of time spent ( E ) and distance traveled ( F ) in the center area are presented. n = 10–12 mice/group. (G-H) A novel object recognition (NOR) test ( G ) was performed to evaluate the preference toward novel object ( H ) in mice treated with or without C6. n = 10–12 mice/group. (I-M) Mice were subjected to the MWM test to assess spatial learning and memory abilities. The me
▸Metadata
| doi | 10.1186/s13024-025-00911-3 |
| pmcid | PMC12639696 |
| _origin | {'url': 'https://www.ebi.ac.uk/europepmc/articles/PMC12639696/bin/13024_2025_911_Fig10_HTML.jpg', 'type': 'external', 'tracked_at': '2026-04-22T22:53:20.577947'} |
| caption | DAPK1 inhibition ameliorates emotional and cognitive impairments in a mouse model of tauopathy. ( A-B) The Y-maze test was applied to evaluate the short-term memory ability in mice treated with or wi |
| paper_id | 22ece900-f8a9-483b-b7ad-9b8d9b45223a |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC12639696/bin/13024_2025_911_Fig10_HTML.jpg |
| image_path | |
| description | |
| figure_label | Fig. 10 |
| figure_number | 10 |
| _schema_version | 1 |
| source_strategy | pmc_api |
| entities_mentioned |
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