🖼
Figure 1.: Alpha-synuclein proteoforms in the appendix and substantia nigra (SN) (A) Bar p...
active
paper figure
Created: 2026-04-28T00:22:23
By: paper_figures_pipeline
Quality:
50%
🔗 External
ID: paper-fig-41279937-1
Figure 1.Figure 1
Alpha-synuclein proteoforms in the appendix and substantia nigra (SN) (A) Bar plot showing 65 alpha-synuclein proteoforms identified in the human appendix and SN. Acetylated proteoforms are colored dark blue; unacetylated proteoforms are colored light blue. Nine proteoforms, which were only found in the appendix, are denoted with *. (B) Bar plot showing alpha-synuclein proteoforms distribution according to their abundance in the human appendix and SN separately. X-axis shows the percentage of the abundance for each existing proteoform. Top 5 most abundant proteoforms are listed with their color codes. (C) Common alpha-synuclein and rare proteoforms showing tissue differences. For common alpha-synuclein proteoforms, robust linear regression was used for statistical analysis adjusting for diagnosis (synucleinopathy/control) and age, with proteoform abundance as dependent variable (Y) and tissue as independent variable (X). Proteoforms showing significant tissue differences after FDR
▸Metadata
| doi | |
| pmcid | PMC12632551 |
| _origin | {'url': 'https://www.ebi.ac.uk/europepmc/articles/PMC12632551/bin/nihpp-2025.10.07.680938v1-f0001.jpg', 'type': 'external', 'tracked_at': '2026-04-28T07:22:23.393405'} |
| caption | Alpha-synuclein proteoforms in the appendix and substantia nigra (SN) (A) Bar plot showing 65 alpha-synuclein proteoforms identified in the human appendix and SN. Acetylated proteoforms are colored d |
| paper_id | 41279937 |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC12632551/bin/nihpp-2025.10.07.680938v1-f0001.jpg |
| image_path | |
| description | |
| figure_label | Figure 1. |
| figure_number | 1 |
| _schema_version | 1 |
| source_strategy | pmc_api |
| entities_mentioned |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.