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Fig. 2: AXL, MERTK, or AM deleted mice were vulnerable to JEV attack with aggravated neu...
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Created: 2026-04-22T18:14:24
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Fig. 2Figure 2
AXL, MERTK, or AM deleted mice were vulnerable to JEV attack with aggravated neuroinflammation. A . AXL −/− , MERTK −/− , AM −/− , and WT mice were infected with JEV at 10 6 PFU. The survival rates of AXL −/− , MERTK −/− and AM −/− mice were all 0%, and that of WT mice was 36%. The median survival times of AXL −/− , MERTK −/− , AM −/− , and WT mice were 5.5, 7.5, 8, and 12 days respectively. B . AXL −/− , MERTK −/− , AM −/− , and WT mice were infected with JEV at 10 5 PFU; the survival proportions of AXL −/− , MERTK −/− , and AM −/− mice were 6.67%, 0%, and 14.29%, while that of WT mice was 38.46%; the median survival times were 7.5, 11, 9, and 15 days, respectively. AXL −/− and WT mice were infected with JEV at 10 6 PFU, and the brains from each group were harvested for HE staining and proinflammatory cytokine detection at 3 and 5 dpi. C . Histopathological changes in the meninges and cerebral cortex in each group. The meninges thickened after JEV infection, as indicated by
▸Metadata
| doi | 10.1186/s12974-024-03225-1 |
| pmcid | PMC11411859 |
| _origin | {'url': 'https://www.ebi.ac.uk/europepmc/articles/PMC11411859/bin/12974_2024_3225_Fig2_HTML.jpg', 'type': 'external', 'tracked_at': '2026-04-23T01:14:24.967469'} |
| caption | AXL, MERTK, or AM deleted mice were vulnerable to JEV attack with aggravated neuroinflammation. A . AXL −/− , MERTK −/− , AM −/− , and WT mice were infected with JEV at 10 6 PFU. The survival rates |
| paper_id | f224acb2-095b-423e-980a-e4cb8c8f61c8 |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC11411859/bin/12974_2024_3225_Fig2_HTML.jpg |
| image_path | |
| description | |
| figure_label | Fig. 2 |
| figure_number | 2 |
| _schema_version | 1 |
| source_strategy | pmc_api |
| entities_mentioned |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
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Incoming
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Outgoing
0
0 supporting
0 contradicting
0 neutral
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