A1 REACTIVE ASTROCYTES

Understanding Entity Pages

This page aggregates everything SciDEX knows about A1 REACTIVE ASTROCYTES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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graph TD
    A1_REACTIVE_ASTROCYTES["A1 REACTIVE ASTROCYTES"]
    A1_REACTIVE_ASTROCYTES -->|"upregulates"| C3["C3"]
    A1_REACTIVE_ASTROCYTES -->|"upregulates"| CXCL10["CXCL10"]
    A1_REACTIVE_ASTROCYTES -->|"downregulates"| Blood_Brain_Barrier_Integrity["Blood-Brain Barrier Integrity"]
    A1_REACTIVE_ASTROCYTES -->|"downregulates"| Blood_Brain_Barrier["Blood-Brain Barrier"]
    A1_REACTIVE_ASTROCYTES -->|"contributes to"| Neuroinflammation["Neuroinflammation"]
    A1_REACTIVE_ASTROCYTES -->|"inhibits"| Neuronal_Survival["Neuronal Survival"]
    A1_REACTIVE_ASTROCYTES -->|"causes"| cognitive_decline["cognitive decline"]
    IL_1_["IL-1alpha"] -->|"activates"| A1_REACTIVE_ASTROCYTES
    TNF["TNF"] -->|"activates"| A1_REACTIVE_ASTROCYTES
    C1q["C1q"] -->|"activates"| A1_REACTIVE_ASTROCYTES