Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ASO: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| SNCA | inhibits | gene | 0.87 |
| ALPHA_SYNUCLEIN | inhibits | protein | 0.87 |
| TDP-43 | targets | protein | 0.75 |
| PARKINSONS_DISEASE | treats | disease | 0.64 |
| Source | Relation | Type | Str |
|---|---|---|---|
| TfR1 | binds | receptor | 0.90 |
Hypotheses where this entity is a therapeutic target
Scientific analyses that reference this entity
neuropharmacology | 2026-04-11 | 0 hypotheses
molecular biology | 2026-04-10 | 0 hypotheses
neuroscience | 2026-04-04 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Gray matter structural and molecular signatures in Alzheimer's disease and late- [PMID:41419068] | Yang S, Wang X, Yan Y, Zhang J, Wei Y et | J Affect Disord | 2026 | 0 |
| Cytomegalic parvalbumin neurons in fetal cases of hemimegalencephaly. [PMID:39973610] | Gelot AB, Draia-Nicolau TO, Mathieu R, S | Epilepsia | 2025 | 0 |
| Brain connectivity and transcriptional changes induced by rTMS in first-episode [PMID:40274783] | Guan M, Xie Y, Wang Z, Miao Y, Li X et a | Transl Psychiatry | 2025 | 0 |
| Single-cell RNA sequencing of adult primate neocortex reveals the regulatory dyn [PMID:40385068] | Zhang C, Xie Z, Wang N | Am J Transl Res | 2025 | 0 |
| Human stem cell-derived GABAergic interneuron development reveals early emergenc [PMID:40651475] | Bershteyn M, Zhou H, Fuentealba L, Chen | Neuron | 2025 | 0 |
| Targeting SARM1 improves autophagic stress-induced axonal neuropathy. [PMID:37561040] | Kim HR, Lee HJ, Jeon Y, Jang SY, Shin YK | Autophagy | 2024 | 0 |
| Integrated multimodal cell atlas of Alzheimer's disease. [PMID:39402379] | Gabitto MI, Travaglini KJ, Rachleff VM, | Nat Neurosci | 2024 | 0 |
| Identification of early Alzheimer's disease subclass and signature genes based o [PMID:39650656] | Wang W, Lu J, Pan N, Zhang H, Dai J et a | Front Immunol | 2024 | 0 |
| Meta-proteomics for the discovery of protein biomarkers of beef tenderness: An o [PMID:31882086] | Picard B, Gagaoua M | Food Res Int | 2020 | 0 |
| Identification of epilepsy-associated neuronal subtypes and gene expression unde [PMID:33028830] | Pfisterer U, Petukhov V, Demharter S, Me | Nat Commun | 2020 | 0 |