gene

BCL2L2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BCL2L2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

BCL2L2 (BCL-W) - anti-apoptotic protein in neuronal survival and development

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🧬 Gene Info

Gene Symbol	BCL2L2
Aliases	BCL-W
Chromosome	14q11.2
Function	is an anti-apoptotic member of the BCL-2 protein family.
Primary Expression	adult tissues with particularly high expression in the brain, spinal cord, and testis
Molecular Weight	20 kDa
Amino Acids	193 aa
Exons	3
UniProt ID	Q92823
NCBI Gene ID	10017
GeneCards	BCL2L2
Human Protein Atlas	BCL2L2
Associated Diseases	Alzheimer's disease, Parkinson's disease, Huntington's disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: BCL2L2 — AlphaFold Q92823 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

BCL2L2 Gene

gene · 1124 words

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Pathway Diagram

graph TD
    BCL2L2["BCL2L2"]
    neurodegeneration["neurodegeneration"]
    BCL2L2 -->|"implicated_in"| neurodegeneration
    style BCL2L2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning BCL2L2 in their description or question text

No additional research found