gene

CNTN6

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CNTN6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

5Connections

0Hypotheses

0Analyses

5Outgoing

0Incoming

0Experiments

Summary

Comprehensive gene page for CNTN6 (Contactin 6), a neural cell adhesion molecule in the immunoglobulin superfamily with roles in neurodevelopment, synaptic function, and disease pathogenesis

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🧬 Gene Info

Gene Symbol	CNTN6
Full Name	Contactin 6
Chromosome	6
Function	is a GPI-anchored membrane protein that mediates cell-cell interactions through homophilic and heterophilic binding mechanisms [@hu2016].
Primary Expression	Brain-enriched
Molecular Weight	107.8 kDa
Amino Acids	193 aa
UniProt ID	Q9UQJ0
NCBI Gene ID	27285
Ensembl ID	ENSG00000134115
GeneCards	CNTN6
Human Protein Atlas	CNTN6
Gene Name	CNTN6 (Contactin 6)
Band	q13
Strand	Plus strand
Associated Diseases	neurodegeneration
Interactions	NOTCH1
KG Connections	5 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CNTN6 — AlphaFold Q9UQJ0 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (5)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    CNTN6["<b>CNTN6</b>"]
    NOTCH1["NOTCH1"]
    CNTN6 -->|"interacts with"| NOTCH1
    CUX1["CUX1"]
    CNTN6 -->|"regulates"| CUX1
    FOXP2["FOXP2"]
    CNTN6 -->|"regulates"| FOXP2
    PVR["PVR"]
    CNTN6 -->|"regulates"| PVR
    MAG["MAG"]
    CNTN6 -->|"upregulates"| MAG
    neurodegeneration["neurodegeneration"]
    CNTN6 -->|"implicated in"| neurodegeneration
    style CNTN6 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (5)

Target	Relation	Type	Str
NOTCH1	interacts_with	gene	0.80
CUX1	regulates	gene	0.70
FOXP2	regulates	gene	0.70
PVR	regulates	gene	0.70
MAG	upregulates	gene	0.70

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

CNTN6

Understanding Entity Pages

Summary

Wiki Pages (5)

CNTN6 — Contactin 6

CNTN5 — Contactin 5

CNTN4 — Contactin 4

FOXP2 Gene