gene

CREB5

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CREB5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

14Connections

0Hypotheses

0Analyses

14Outgoing

0Incoming

Summary

Page for CREB5 — cAMP Responsive Element Binding Protein 5

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🧬 Gene Info

Gene Symbol	CREB5
Full Name	CREB5 — cAMP Responsive Element Binding Protein 5
Aliases	cAMP Responsive Element Binding Protein 5
Chromosome	7p15.1
Protein Type	Gene
Function	Like other CREB family members, CREB5 contains a basic leucine zipper (bZIP) domain that facilitates DNA binding and protein dimerization 5.
Primary Expression	brain regions involved in learning and memory
Pathways	Angiogenesis, Dna Methylation, Epigenetic
NCBI Gene ID	Search NCBI
GeneCards	CREB5
Human Protein Atlas	CREB5
Associated Diseases	Common Diseases, Complex Human Diseases
Interactions	MYH7, FOXO3
KG Connections	14 knowledge graph edges
Databases	GeneCards UniProt HPA STRING

Wiki Pages (6)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    CREB5["<b>CREB5</b>"]
    Als{"Als"}
    CREB5 -->|"regulates"| Als
    Ms{"Ms"}
    CREB5 -->|"regulates"| Ms
    MYH7["MYH7"]
    CREB5 -->|"activates"| MYH7
    FOXO3["FOXO3"]
    CREB5 -->|"activates"| FOXO3
    EXERCISE["EXERCISE"]
    CREB5 -->|"regulates"| EXERCISE
    Epigenetic(["Epigenetic"])
    CREB5 -->|"regulates"| Epigenetic
    Dna_Methylation(["Dna Methylation"])
    CREB5 -->|"regulates"| Dna_Methylation
    Angiogenesis(["Angiogenesis"])
    CREB5 -->|"regulates"| Angiogenesis
    neurodegeneration["neurodegeneration"]
    CREB5 -->|"implicated in"| neurodegeneration
    style CREB5 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (14)

Target	Relation	Type	Str
Cell Types	expressed_in	cell_type	0.80
Muscle Fibers	expressed_in	cell_type	0.70
Plasma Proteome	associated_with	biological_process	0.70
Complex Human Diseases	associated_with	disease	0.70
Common Diseases	associated_with	disease	0.70
Als	regulates	disease	0.65
Ms	regulates	disease	0.65
MYH7	activates	gene	0.60
FOXO3	activates	gene	0.60
Cardiac Repolarization	participates_in	biological_process	0.60
EXERCISE	regulates	gene	0.60
Epigenetic	regulates	pathway	0.60
Dna Methylation	regulates	pathway	0.60
Angiogenesis	regulates	pathway	0.60

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

CREB5

Understanding Entity Pages

Summary

Wiki Pages (6)

CREB5 — cAMP Responsive Element Binding Protein 5

Cell Types

MYH7 Gene

CREB5 Protein — cAMP Responsive Element Binding Protein 5