Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Calcium Dynamics: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| TRPML1 | regulates | gene | 0.95 |
| TRPV4 | regulates | gene | 0.90 |
| Calcium-Associated Proteins | regulates | protein | 0.90 |
| TRPV4 | regulates | gene | 0.90 |
| Calcium-Binding Proteins | regulates | protein | 0.88 |
| calcium-binding proteins | modulates | protein | 0.85 |
| Caldendrin | regulates | protein | 0.80 |
| Piezo1 | regulates | protein | 0.80 |
| TRPA1 | regulates | gene | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| TREM2-Regulated Astrocytic Calcium Dynamics Control Glymphat | 0.380 | neuroscience | TREM2 in Alzheimer's Disease: Mechanisms |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| The Role of Exercise in Regulating Brain Health and Aging through Glymphatic Fun [PMID:41467766] | Wang J, Li J | The Neuroscientist : a review | 2026 | 0 |
| Modulating glymphatic clearance in Alzheimer's disease: Molecular mechanisms, im [PMID:41763274] | ["Oriquat Ghaleb", "Ali Afaq Mahdi", "Pa | Behavioural brain research | 2026 | 0 |
| Selective removal of astrocytic PERK protects against glymphatic impairment and [PMID:40403715] | Chen K, Morizawa YM, Nuriel T, Al-Dalahm | Neuron | 2025 | 0 |
| High-intensity interval training ameliorates Alzheimer's disease-like pathology [PMID:37351177] | Feng S, Wu C, Zou P, Deng Q, Chen Z, Li | Theranostics | 2023 | 0 |
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning Calcium Dynamics in their description or question text
No additional research found