Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Cell-type specific vulnerability markers: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| neurodegeneration | associated_with | disease | 0.50 |
| TNFRSF25 | co_associated_with | gene | 0.40 |
| Mitochondrial respiratory complexes and inflammatory cytokine receptors | co_associated_with | gene | 0.40 |
| PFN1 | co_associated_with | gene | 0.40 |
| Source | Relation | Type | Str |
|---|---|---|---|
| AP1S1 | co_associated_with | gene | 0.40 |
| CGAS, STING1 | co_associated_with | gene | 0.40 |
| CXCL10 | co_associated_with | gene | 0.40 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Selective Neuronal Vulnerability Network Targeting | 0.431 | neurodegeneration | Gene expression changes in aging mouse b |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-03 | 34 hypotheses Top: 0.692
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Multiomics Profiling of T-cell Leukemia and Lymphoma Enables Targeted Therapeuti [PMID:41166698] | Ianevski A, Nader K, Nguyen J, Sorger H, | Cancer Res | 2026 | 0 |
| Outer retinal tubulation associated with photoreceptor degeneration. [PMID:41548710] | Lin V, Lee W, Kang EY, Liu PK, Wang NK | Prog Retin Eye Res | 2026 | 0 |
| Therapeutic targeting of cancer stem cell-specific surface glycans and glycoprot [PMID:41667793] | Al-Khreisat MJ, Abdulsahib WK, Jasim IK, | Discov Oncol | 2026 | 0 |
| Modest neurodevelopment impacts of APOE4 in a human brain organoid model of low- [PMID:41697903] | Muniz-Perez A, Meyer-Acosta KK, Boyana S | Dev Neurosci | 2026 | 0 |
| Dual roles of basal NLRP3 expression in cognitive and neurogenic aging. [PMID:41779054] | Komleva YK, Khilazheva ED, Mosiagina AI, | Biogerontology | 2026 | 0 |
| Breast tumour-secreted ADAM10 mediates atrial fibrogenesis and fibrillation. [PMID:41780910] | Xue G, Zhang P, Zhan G, Wang X, Dong H e | Eur Heart J | 2026 | 0 |
| Immunohistochemical Markers of Mitochondrial Electron Transport Chain Instabilit [PMID:41898675] | Baranich TI, Sukhorukov VS, Velts OV, Vo | Int J Mol Sci | 2026 | 0 |
| Ageing-related structural and cellular alterations in the mouse muscle-tendon ju [PMID:41935232] | Thorpe CT, Iwasaki N | Biogerontology | 2026 | 0 |
| Cell line-specific modulation of inflammation by oestradiol in an in vitro model [PMID:41360307] | Kirkpatrick M, Alboni S, Imbeni F, Maria | Brain, behavior, and immunity | 2026 | 0 |