Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GD3 SYNTHASE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GD3 SYNTHASE |
| Key Genes/Proteins | AMYLOID-BETA |
Knowledge base pages for this entity
graph TD
GD3_SYNTHASE["GD3 SYNTHASE"]
GD3_SYNTHASE -->|"catalyzes"| Gd3["Gd3"]
GD3_SYNTHASE -->|"catalyzes"| Ganglioside_Biosynthesis["Ganglioside Biosynthesis"]
GD3_SYNTHASE -.protects against.-> Parkinsonism["Parkinsonism"]
GD3_SYNTHASE -.protects against.-> Executive_Dysfunction["Executive Dysfunction"]
GD3_SYNTHASE -->|"regulates"| Gm1["Gm1"]
GD3_SYNTHASE -->|"regulates"| Gangliosides["Gangliosides"]
GD3_SYNTHASE -->|"mediates"| Neuroprotection["Neuroprotection"]
GD3_SYNTHASE -->|"reduces"| amyloid_beta_plaque["amyloid-beta plaque"]
ST8SIA1["ST8SIA1"] -->|"encodes"| GD3_SYNTHASE
ASTROCYTE["ASTROCYTE"] -->|"interacts"| GD3_SYNTHASE| Target | Relation | Type | Str |
|---|---|---|---|
| AMYLOID-BETA | regulates | protein | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ST8SIA1 | associated_with | gene | 0.95 |
| ST8SIA1 | expressed_in | gene | 0.90 |
| ASTROCYTE | interacts_with | cell_type | 0.70 |
| benchmark_ot_ad_answer_key:GD3 SYNTHASE | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||