gene

IFFO1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about IFFO1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

IFFO1 encodes an intermediate filament protein involved in nuclear envelope organization and neuronal function

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🧬 Gene Info

Gene Symbol	IFFO1
Full Name	IFFO1 — Intermediate Filament Family Orphan 1
Chromosome	6p21.1
Protein Type	Gene
Function	is a human gene encoding a protein belonging to the intermediate filament family[@snyman1995].
Primary Expression	various tissues, including the brain, where it localizes primarily to the nuclear envelope
Subcellular Localization	- Nuclear envelope: Primary localization
Molecular Weight	50 kDa
Amino Acids	462 aa
Exons	12
NCBI Gene ID	Search NCBI
GeneCards	IFFO1
Human Protein Atlas	IFFO1
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards UniProt HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

IFFO1 — Intermediate Filament Family Orphan 1

gene · 1263 words

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Genes

index · 271 words

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Pathway Diagram

graph TD
    IFFO1["IFFO1"]
    neurodegeneration["neurodegeneration"]
    IFFO1 -->|"implicated_in"| neurodegeneration
    style IFFO1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found